Collection: Mary & May

Spicules are microscopic needle-like structures from marine sponges (Spongilla) that create temporary micro-channels in the skin's surface when massaged in — effectively delivering active ingredients (collagen, retinol, PDRN, peptides) deeper into the skin than topical application alone could achieve. The Spicule line includes Collagen PDRN Cream and Retinol PDRN Cream, both of which pair the physical delivery technology with biological actives for visible firming and anti-aging results. Apply the cream and massage gently for 30–60 seconds to activate the spicules. May feel slightly tingling on first uses.

Mary & May stands out for three reasons: eco-conscious packaging (recyclable materials, minimalist design), 100% vegan formulations (no animal-derived ingredients across the range), and EWG-green-grade ingredient transparency (most products score the highest EWG safety grades). The brand is also known for hidden-gem products like the Glutathione Eye Cream Set (clinical-strength brightening for the eye area) and the Idebenone Blackberry Intense Cream (idebenone is a potent antioxidant similar to CoQ10).

Mary & May offers multiple wash-off masks (Rose Hyaluronic Hydra, CICA Tea Tree, Vegan Wash-Off Mask Mini Set) and sheet masks (Vegan Collagen Red Ginseng, Charcoal PDRN, Fresh Aloe). Wash-off masks are best used 1–3 times per week as a treatment step. Sheet masks can be used 2–4 times per week or even nightly for a 'mask-fasting' challenge. Choose the variant based on your concern: Red Ginseng for anti-aging, Charcoal PDRN for pore care + regeneration, Fresh Aloe for calming, Rose Hyaluronic for hydration, CICA Tea Tree for breakouts.

Idebenone is a synthetic analog of CoQ10 — one of the most powerful antioxidants used in skincare, with documented benefits in fighting free radical damage, reducing oxidative stress and supporting anti-aging. The Idebenone Blackberry Intense Cream combines idebenone with blackberry (rich in additional antioxidants like anthocyanins and vitamin C) for a comprehensive anti-aging treatment. The cream targets fine lines, dullness and environmental damage, making it ideal for users in polluted urban environments or sun-exposed climates like the UAE/GCC.

Glutathione is a naturally occurring antioxidant compound in the body and is generally considered safe for topical use during pregnancy and breastfeeding — unlike retinol-based eye creams which should be avoided during these periods. The Mary & May Glutathione Eye Cream Set delivers brightening, firming and antioxidant benefits without the contraindications of retinol. Always check the full INCI list and consult your obstetrician about any product use during pregnancy. Avoid the Spicule Retinol PDRN Cream during pregnancy/breastfeeding — choose the Spicule Collagen PDRN Cream instead.