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Shop the PDRN Collection for deep hydration, firmness and a smooth, plump glow – for all skin types

Collection: PDRN Skincare Products | Anti-Aging Serums & Treatments

Discover the power of PDRN (Polydeoxyribonucleotide) — the cutting-edge K-Beauty ingredient transforming millions of complexions worldwide. Traditionally sourced from salmon DNA, PDRN supports skin renewal, helps boost collagen production and improves firmness, working at the cellular level to restore elasticity and luminosity naturally. Our curated collection of 134+ PDRN products combines Korean innovation with dermatological excellence for visible results.

Problems This Solves

  • PDRN helps visibly improve fine lines, wrinkles, dark circles, loss of elasticity, uneven skin tone, dullness and tired-looking skin by supporting collagen and restoring radiance for firmer, brighter, more youthful-looking skin.

Key Benefits You'll Get

  • Expect smoother, firmer-looking skin, restored youthful radiance, natural firming and lifting, a glass-skin finish, and long-lasting hydration that helps skin feel plump and comfortable.

Shop PDRN by Category

Pairs Well With

Best-Selling Brands

  • Shop trusted PDRN lines from Medicube with 125+ products, Some By Mi for affordable excellence, and COSRX for clinical-grade formulas.

How to Use

Frequently Asked Questions

What is PDRN in skincare?

PDRN (Polydeoxyribonucleotide) is a nucleotide-derived ingredient, traditionally sourced from salmon DNA, used in K-Beauty to support skin renewal, hydration and firmness for a healthier, more youthful-looking complexion.

What does PDRN do for the skin?

PDRN helps support collagen production, improve elasticity and boost hydration. It's popular for targeting fine lines, dullness and loss of firmness, helping skin look smoother, plumper and more radiant.

Is PDRN suitable for sensitive skin?

PDRN is generally gentle and well-tolerated, making it a popular choice for most skin types. If you have sensitive or reactive skin, introduce it slowly and patch-test first, or explore our sensitive skin collection.

How long does PDRN take to show results?

With consistent daily use, many people notice smoother, more hydrated skin within a few weeks, while firmness and tone typically improve over 4 to 6 weeks of regular use.

Can I use PDRN with other ingredients?

Yes. PDRN pairs well with hyaluronic acid, niacinamide, peptides and centella. Introduce strong actives like retinol or acids gradually to avoid irritation.

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146 products

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Big Saving On Holiday Sets
Mary&May Vegan Collagen Charcoal PDRN Mask — vegan collagen charcoal PDRN sheet mask

Mary&May Vegan Collagen Charcoal PDRN Mask

Regular price
Sale price Dhs. 160.00 AED Regular price Dhs. 190.00 AED
Purito Seoul Oat PDRN Gentle Refining Toner — oat PDRN gentle refining toner

Purito Seoul Oat PDRN Gentle Refining Toner

Regular price
Sale price Dhs. 170.00 AED Regular price Dhs. 180.00 AED
Abib_PDRN_Vegan_Collagen_lip_mask_Glazed_jelly

Abib PDRN Collagen Lip Mask Jelly

Regular price
Sale price Dhs. 170.00 AED Regular price Dhs. 210.00 AED
Medicube PDRN Pink Glow Kit

Medicube PDRN Pink Glow Kit

Regular price
Sale price Dhs. 170.00 AED Regular price Dhs. 200.00 AED
Medicube PDRN Pink Collagen Bubble Serum for firming, elasticity and glow

Medicube PDRN Pink Collagen Bubble Serum

Regular price
Sale price Dhs. 200.00 AED Regular price Dhs. 240.00 AED
Medicube PDRN Peptide Glossy Lip Balm for glossy, plump and nourished lips

Medicube PDRN Peptide Glossy Lip Balm

Regular price Dhs. 140.00 AED
Sale price Regular price
EQQUALBERRY Aloe PDRN Calming Serum 30ml

EQQUALBERRY GREEN AID Aloe PDRN Calming Serum

Regular price
Sale price Dhs. 210.00 AED Regular price Dhs. 240.00 AED
Numbuzin No.2 Rose PDRN Collagen Plumping Serum Duo — rose PDRN collagen plumping serum duo set

Numbuzin No.2 Rose PDRN Collagen Plumping Serum Duo

Regular price
Sale price Dhs. 160.00 AED Regular price Dhs. 220.00 AED
PRETTYSKIN PDRN TX1 Perfect Fit Serum – revitalizing PDRN serum

PRETTYSKIN PDRN TX1 Perfect fit Serum

Regular price
Sale price Dhs. 160.00 AED Regular price Dhs. 190.00 AED
PRETTYSKIN PDRN TX1 Perfect Fit Cream – revitalizing PDRN cream

PRETTYSKIN PDRN TX1 Perfect Fit Cream

Regular price
Sale price Dhs. 190.00 AED Regular price Dhs. 220.00 AED
PRETTYSKIN NMD+PDRN Biotox Facial Cream – regenerating anti-aging cream

PRETTYSKIN NMD+PDRN Biotox Facial Cream

Regular price
Sale price Dhs. 199.00 AED Regular price Dhs. 250.00 AED
Medicube PDRN Pink Caffeine Overnight Wrapping Mask, a Korean peel-off sleeping mask

Medicube PDRN Pink Caffeine Overnight Wrapping Mask

Regular price Dhs. 105.00 AED
Sale price Regular price
VT Cosmetics PDRN Essence Stick Balm

VT Cosmetics PDRN Essence Stick Balm

Regular price
Sale price Dhs. 170.00 AED Regular price Dhs. 180.00 AED
Numbuzin No.9 NAD PDRN Glow Boosting Toner — NAD and PDRN glow-boosting toner

Numbuzin No.9 NAD PDRN Glow Boosting Toner

Regular price
Sale price Dhs. 160.00 AED Regular price Dhs. 210.00 AED
Numbuzin No.2 Rose PDRN Collagen 2X Plumping Serum — double-strength rose PDRN collagen serum

Numbuzin No.2 Rose PDRN Collagen 2X Plumping Serum

Regular price
Sale price Dhs. 160.00 AED Regular price Dhs. 244.00 AED
Numbuzin No.2 Rose PDRN Collagen Plumping Serum — rose PDRN and collagen plumping serum

Numbuzin No.2 Rose PDRN Collagen Plumping Serum

Regular price
Sale price Dhs. 160.00 AED Regular price Dhs. 220.00 AED
VT Cosmetics PDRN Reedle Shot 100

VT Cosmetics PDRN Reedle Shot 100

Regular price
Sale price Dhs. 180.00 AED Regular price Dhs. 210.00 AED
VT Cosmetics PDRN Reedle Shot 300

VT Cosmetics PDRN Reedle Shot 300

Regular price
Sale price Dhs. 185.00 AED Regular price Dhs. 230.00 AED
Isntree Gim PDRN Hydro Bouncy Ampoule — plumps skin for a smooth, bouncy finish

Isntree Gim PDRN Hydro Bouncy Ampoule

Regular price
Sale price Dhs. 160.00 AED Regular price Dhs. 210.00 AED
Isntree GIM PDRN Deep Sleep Mask — PDRN supports overnight skin repair and resilience

Isntree GIM PDRN Deep Sleep Mask

Regular price
Sale price Dhs. 180.00 AED Regular price Dhs. 250.00 AED
Medicube PDRN Pink Vita Coating Sheet Mask, a Korean pink sheet mask for glowing skin

Medicube PDRN Pink Vita Coating Mask

Regular price
Sale price Dhs. 15.00 AED Regular price Dhs. 30.00 AED
VT Cosmetics PDRN Reedle Shot Cream

VT Cosmetics PDRN Reedle Shot Cream

Regular price
Sale price Dhs. 180.00 AED Regular price Dhs. 230.00 AED
Medicube PDRN Pink Niacinamide Whip Cleanser 120g, a gentle whipped cream cleanser for bright, soft skin

Medicube PDRN Pink Niacinamide Whip Cleanser

Regular price
Sale price Dhs. 170.00 AED Regular price Dhs. 200.00 AED
Medicube PDRN Pink Tone-Up Sun Cream 50ml, a lightweight tone-up sunscreen with a natural peachy glow

Medicube PDRN Pink Tone-Up Sun Cream

Regular price
Sale price Dhs. 190.00 AED Regular price Dhs. 210.00 AED
Medicube PDRN Pink Niacinamide Milky Toner 150ml, a milky hydrating toner essence for a bright, dewy complexion

Medicube PDRN Pink Niacinamide Milky Toner

Regular price
Sale price Dhs. 180.00 AED Regular price Dhs. 200.00 AED
EQQUALBERRY Purple PDRN Pore Minimizing Serum

EQQUALBERRY PORE FIT Purple PDRN Pore Minimizing Serum

Regular price
Sale price Dhs. 190.00 AED Regular price Dhs. 210.00 AED
Medicube PDRN Pink Collagen Toning Gel Toner Pad, a Korean jelly toner pad for glowing skin

Medicube PDRN Pink Toning Gel Toner Pad

Regular price Dhs. 200.00 AED
Sale price Regular price
Medicube PDRN Pink Exosome Shot Serum 2000

Medicube PDRN Pink Exosome Shot Serum 2000

Regular price
Sale price Dhs. 170.00 AED Regular price Dhs. 200.00 AED
Medicube PDRN Pink Peptide Eye Cream 30ml, an all-in-one eye cream for fine lines and firmness

Medicube PDRN Pink Peptide Eye Cream

Regular price
Sale price Dhs. 210.00 AED Regular price Dhs. 240.00 AED
Medicube PDRN Pink Collagen Capsule Cream, a Korean dual-texture cream for even, glowing skin

Medicube PDRN Pink Collagen Capsule Cream

Regular price
Sale price Dhs. 210.00 AED Regular price Dhs. 240.00 AED
Medicube PDRN Lip Sleeping Mask, Korean overnight lip mask with salmon PDRN and collagen

Medicube PDRN Lip Sleeping Mask

Regular price Dhs. 79.00 AED
Sale price Regular price
VT Cosmetics PDRN Essence 100

VT Cosmetics PDRN Essence 100

Regular price
Sale price Dhs. 170.00 AED Regular price Dhs. 210.00 AED
Medicube PDRN Pink Exosome Shot Serum 7500

Medicube PDRN Pink Exosome Shot Serum 7500

Regular price
Sale price Dhs. 200.00 AED Regular price Dhs. 240.00 AED
Medicube PDRN Pink One Day Serum Set

Medicube PDRN Pink One Day Serum Set

Regular price
Sale price Dhs. 158.00 AED Regular price Dhs. 160.00 AED
Medicube PDRN Booster Gel

Medicube PDRN Booster Gel

Regular price
Sale price Dhs. 210.00 AED Regular price Dhs. 240.00 AED